The study investigated the availability and utilization of digital strategies for preventing examination malpractice in biology examinations in senior secondary schools in Nsukka Local Government Area, Enugu state. It was guided by four specific purposes; and employed descriptive survey research design. 332 Biology students and 9 Biology teachers were sampled. Data were collected using face-validated checklist and rating scale; with reliability indices of 0.83, 0.81 and 0.76 ascertained using Cronbach Alpha. Data were analyzed using descriptive statistics. Results showed that digital strategies for preventing examination malpractice were not available except for biometric verification devices for candidates' identification. Also, digital strategies were used at low extent. Among the challenges limiting effective utilization of digital strategies for preventing examination malpractice were inadequate digital tools and insufficient training of Biology teachers on the use of digital strategies; while provision of sufficient digital equipment and organizing regular ICT training for teachers among others are solutions to the challenges identified.